IMEMR
66.92
Volume 3, Issue 1 (2022)                   J Clinic Care Skill 2022, 3(1): 31-36 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hosseini M, Mohammadi B, Mohammadi J. Serum Leptin, Plasma Glucose, and Lactate Changes following Aerobic Exhaustive Incremental Exercise in Trained 18-26 Years Old Men. J Clinic Care Skill 2022; 3 (1) :31-36
URL: http://jccs.yums.ac.ir/article-1-128-en.html
1- Department of Physical Education, Faculty of Physical Education, Farhangian University of Kerman, Kerman, Iran
2- Department of Pediatrics, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran
3- Department of Physiology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran , j.mohammadi.4554@gmail.com
Abstract:   (1348 Views)
Aims: This study aimed to examine the acute effects of exhaustive incremental exercise on serum leptin, glucose, and lactate in one session in trained 18-26 years old men.
Material & Methods: The present study was conducted in 2021 on male physical education students available at the Faculty of Sports Sciences of the Shahid Chamran University of Ahvaz in Iran. Thirty students who had 18-26 years old, with body fat between 15-25% and VO2max between 35-45ml/kg/min, were simple randomly selected through 200 physical education students, and they were divided into two equal training and the control groups (each of them consists of 15 subjects). The exercise test included the Astrand test on a treadmill that performed exhaustive incremental exercise. Blood samples have been collected from two groups in pre and post-test and 9 hours after exhaustive incremental exercise. The statistical analyses used were the Independent T-test and one-way ANOVA tests by SPSS version 20.
Findings: Results showed that serum leptin did not change between three measurement sets in the training group in comparison to the control group (p>0.05). Plasma glucose significantly changed between pre and post-test and pretest and 9 hours later (p<0.001). Plasma lactate significantly changed in post-test in comparison to pretest and 9 hours later to post-test (p<0.001).
Conclusion: Incremental exhaustive exercise has no significant effect on serum leptin.
 
Full-Text [PDF 829 kb]   (1101 Downloads)    
Article Type: Original Research | Subject: Special
Received: 2022/02/2 | Accepted: 2022/03/1 | Published: 2022/03/12

References
1. Bouassida A, Zalleg D, Bouassida S, Zaouali M, Feki Y, Zbidi A, Tabka Z. Leptin, its implication in physical exercise and training: a short review. J Sports Sci Med. 2006;5(2):172-81. [link]
2. Baile CA, Della-Fera MA, Martin RJ. Regulation of metabolism and body fat mass by leptin. Annu Rev Nutr. 2000;20:105-27. [DOI:10.1146/annurev.nutr.20.1.105] [PMID]
3. Bryson JM, Phuyal JL, Swan V, Caterson ID. Leptin has acute effects on glucose and lipid metabolism in both lean and gold thioglucose-obese mice. Am J Physiol. 1999;277(3):E417-22. [DOI:10.1152/ajpendo.1999.277.3.E417] [PMID]
4. Chwalbinska-Moneta J, Krysztofiak F, Ziemba A, Nazar K, Kaciuba-Uściłko H. Threshold increases in plasma growth hormone in relation to plasma catecholamine and blood lactate concentrations during progressive exercise in endurance-trained athletes. Eur J Appl Physiol Occupational Physiol. 1996;73(1-2):117-20. [DOI:10.1007/BF00262819] [PMID]
5. Dirlewanger M, Di Vetta V, Giusti V, Schneiter P, Jéquier E, Tappy L. Effect of moderate physical activity on plasma leptin concentration in humans. Eur J Appl Physiol Occupat Physiol. 1999;79(4):331-5. [DOI:10.1007/s004210050516] [PMID]
6. Duclos M, Corcuff JB, Ruffie A, Roger P, Manier G. Rapid leptin decrease in immediate post‐exercise recovery. Clin Endocrinol. 1999;50(3):337-42. [DOI:10.1046/j.1365-2265.1999.00653.x] [PMID]
7. Sajedi D, Shabani R, Elmieh A. Changes in leptin, serotonin, and cortisol after eight weeks of aerobic exercise with probiotic intake in a cuprizone-induced demyelination mouse model of multiple sclerosis. Cytokine. 2021;144:155590. [DOI:10.1016/j.cyto.2021.155590] [PMID]
8. Kharaeva Z, Hokonova T, Elmurzaeva J, Dzamihova I, Mayer W, De Luca C, et al. Effects of heavy isotopes (2H1 and 18O16) depleted water con-sumption on physical recovery and metabolic and immunological parameters of healthy volunteers under regular fitness load Sports. 2021;9(8):110. [DOI:10.3390/sports9080110] [PMID] [PMCID]
9. De Groote E, Deldicque L. Is physical exercise in hypoxia an interesting strategy to prevent the development of type 2 diabetes? a narrative review. Diabetes Metab Syndr Obes. 2021;14:3603-16. [DOI:10.2147/DMSO.S322249] [PMID] [PMCID]
10. Kim DS, Wheeler MT, Ashley EA. The genetics of human performance. Nat Rev Genet. 2022;23(1):40-54. [DOI:10.1038/s41576-021-00400-5] [PMID]
11. Houmard JA, Cox JH, MacLean PS, Barakat HA. Effect of short-term exercise training on leptin and insulin action. Metabolism. 2000;49(7):858-61. [DOI:10.1053/meta.2000.6751] [PMID]
12. Fisher JS, Van Pelt RE, Zinder O, Landt M, Kohrt WM. Acute exercise effect on postabsorptive serum leptin. J Appl Physiol. 2001;91(2):680-6. [DOI:10.1152/jappl.2001.91.2.680] [PMID]
13. Nindl BC, Kraemer WJ, Arciero PJ, Samatallee N, Leone CD, Mayo MF, et al. Leptin concentrations experience a delayed reduction after resistance exercise in men. Med Sci Sports Exerc. 2002;34(4):608-13. https://doi.org/10.1097/00005768-200204000-00008 [DOI:10.1249/00005768-200204000-00008] [PMID]
14. Hilton LK, Loucks AB. Low energy availability, not exercise stress, suppresses the diurnal rhythm of leptin in healthy young women. Am J Physiol Endocrinol Metab. 2000;278(1):E43-9. [DOI:10.1152/ajpendo.2000.278.1.E43] [PMID]
15. Pérusse L, Collier G, Gagnon J, Leon AS, Rao DC, Skinner JS, et al. Acute and chronic effects of exercise on leptin levels in humans. J Appl Physiol. 1997;83(1):5-10. [DOI:10.1152/jappl.1997.83.1.5] [PMID]
16. Elias AN, Pandian MR, Wang L, Suarez E, James N, Wilson AF. Leptin and IGF-I levels in unconditioned male volunteers after short-term exercise. Psychoneuroendocrinology. 2000;25(5):453-61. [DOI:10.1016/S0306-4530(99)00070-0]
17. Landt M, Lawson GM, Helgeson JM, Davila-Roman VG, Ladenson JH, Jaffe AS, et al. Prolonged exercise decreases serum leptin concentrations. Metabolism. 1997;46(10):1109-12. [DOI:10.1016/S0026-0495(97)90200-6]
18. Leal-Cerro A, Garcia-Luna PP, Astorga R, Parejo J, Peino R, Dieguez C, et al. Serum leptin levels in male marathon athletes before and after the marathon run. J Clin Endocrinol Metab. 1998;83(7):2376-9. https://doi.org/10.1210/jcem.83.7.4959 [DOI:10.1210/jc.83.7.2376] [PMID]
19. Olive JL, Miller GD. Differential effects of maximal-and moderate-intensity runs on plasma leptin in healthy trained subjects. Nutrition. 2001;17(5):365-9. [DOI:10.1016/S0899-9007(01)00522-6]
20. Zaccaria M, Ermolao A, Roi G, Englaro P, Tegon G, Varnier M. Leptin reduction after endurance races differing in duration and energy expenditure. Eur J Appl Physiol. 2002;87(2):108-11. [DOI:10.1007/s00421-002-0606-4] [PMID]
21. Al-Hussaniy HA, Alburghaif AH, Naji MA. Leptin hormone and its effectiveness in reproduction, metabolism, immunity, diabetes, hopes and ambitions. J Med Life. 2021;14(5):600-5. [DOI:10.25122/jml-2021-0153] [PMID] [PMCID]
22. Picó C, Palou M. Leptin and metabolic programming. Nutrients. 2022;14(1):114. [DOI:10.3390/nu14010114] [PMID] [PMCID]
23. Suzuki Y, Takagishi K, Kurose Y. Circadian rhythm in hypothalamic leptin receptor (Ob-Rb) mRNA expressions and cerebrospinal fluid and circulating glucose and leptin levels in lactating rats. Biochem Biophys Rep. 2021;28:101129. [DOI:10.1016/j.bbrep.2021.101129] [PMID] [PMCID]
24. Hickey MS, Calsbeek DJ. Plasma leptin and exercise. Sports Med. 2001;31(8):583-9. [DOI:10.2165/00007256-200131080-00003] [PMID]
25. Goral M. Effects of leptin, diet and various exercises on the obesity. Res J Biol Sci. 2008;3(11):1356-64. [link]
26. Racette SB, Coppack SW, Landt M, Klein S. Leptin production during moderate-intensity aerobic exercise. J Clin Endocrinol Metab. 1997;82(7):2275-7. https://doi.org/10.1210/jcem.82.7.4037 [DOI:10.1210/jc.82.7.2275] [PMID]
27. Ramírez-Vélez R, García-Hermoso A, Correa-Rodríguez M, Fernández-Irigoyen J, Palomino-Echeverría S, Santamaría E, et al. Effects of different doses of exercise on inflammation markers among adolescents with overweight/obese: HEPAFIT study. J Clin Endocrinol Metab. 2022:dgac021. [DOI:10.1210/clinem/dgac021] [PMID]
28. Reseland JE, Anderssen SA, Solvoll K, Hjermann I, Urdal P, Holme I, et al. Effect of long-term changes in diet and exercise on plasma leptin concentrations. Am J Clin Nutr. 2001;73(2):240-5. [DOI:10.1093/ajcn/73.2.240] [PMID]
29. Thong FS, Hudson R, Ross R, Janssen IA, Graham TE. Plasma leptin in moderately obese men: independent effects of weight loss and aerobic exercise. Am J Physiol Endocrinol Metabo. 2000;279(2):E307-13. [DOI:10.1152/ajpendo.2000.279.2.E307] [PMID]
30. Weltman A, Pritzlaff CJ, Wideman L, Considine RV, Fryburg DA, Gutgesell ME, et al. Intensity of acute exercise does not affect serum leptin concentrations in young men. Med Sci Sports Exercise. 2000;32(9):1556-61. [DOI:10.1097/00005768-200009000-00005] [PMID]
31. Trayhurn P, Hoggard N, Mercer JG, Rayner DV. Hormonal and neuroendocrine regulation of energy balance‐the role of leptin. Archiv für Tierernaehrung. 1998;51(2-3):177-85. [DOI:10.1080/17450399809381917] [PMID]

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.